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KMID : 1094020140310040350
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Journal of Veterinary Clinics
2014 Volume.31 No. 4 p.350 ~ p.353
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Bradycardia after Dobutamine Administration in a Dog
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Jang Min
Son Won-Gyun
Hwang Hye-Shin
Jo Sang-min
Yi Kang-jae
Yoon Jung-Hee
Lee In-Hyung
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Abstract
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A 13-year-old, castrated male, Shih Tzu dog with a history of acute ataxia was referred to veterinary medicalteaching hospital and anesthetized for diagnostic magnetic resonance imaging of cervical intervertebral disk disease. After preanesthetic evaluation including physical examination, blood chemistry, radiography and ultrasound, the patientwas premedicated with intravenous butorphanol (0.2 mg/kg). Anesthesia was induced by intravenous propofol (6 mg/kg) and maintained with isoflurane at 1.2 minimal alveolar concentrations. Because the mean arterial pressure (MAP)decreased from 70 to 58 mmHg at 70 minutes after induction, dobutamine was administered by constant rate infusion(5 μg/kg/min) to treat hypotension. However MAP did not increase, and heart rate rapidly decreased from 100 to 55beats per minute (bpm). To treat bradycardia, intravenous glycopyrrolate (5 μg/kg) was administered, and heart rateincreased to 165 bpm. After extubation of endotracheal tube, the patient showed normal recovery without any problemsrelated to cardiovascular system. Unexpected dobutamine-induced bradycardia was considered as Bezold-Jarisch reflex. It is recommended that clinicians know and prepare the possibility of bradycardia during dobutamine therapy undergeneral anesthesia.
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KEYWORD
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hypotension, dobutamine, bradycardia, Bezold-Jarisch reflex, dog
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